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Dissection of Signaling Events Downstream of the c-Mpl Receptor in Murine Hematopoietic Stem Cells Via Motif-Engineered Chimeric Receptors

Hematopoietic stem cells (HSCs) are a valuable resource in transplantation medicine. Cytokines are often used to culture HSCs aiming at better clinical outcomes through enhancement of HSC reconstitution capability. Roles for each signal molecule downstream of receptors in HSCs, however, remain puzzl...

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Détails bibliographiques
Publié dans:Stem Cell Rev
Auteurs principaux: Saka, Koichiro, Lai, Chen-Yi, Nojima, Masanori, Kawahara, Masahiro, Otsu, Makoto, Nakauchi, Hiromitsu, Nagamune, Teruyuki
Format: Artigo
Langue:Inglês
Publié: Springer US 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801400/
https://ncbi.nlm.nih.gov/pubmed/28948469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-017-9768-7
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