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Dissection of Signaling Events Downstream of the c-Mpl Receptor in Murine Hematopoietic Stem Cells Via Motif-Engineered Chimeric Receptors

Hematopoietic stem cells (HSCs) are a valuable resource in transplantation medicine. Cytokines are often used to culture HSCs aiming at better clinical outcomes through enhancement of HSC reconstitution capability. Roles for each signal molecule downstream of receptors in HSCs, however, remain puzzl...

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Dades bibliogràfiques
Publicat a:Stem Cell Rev
Autors principals: Saka, Koichiro, Lai, Chen-Yi, Nojima, Masanori, Kawahara, Masahiro, Otsu, Makoto, Nakauchi, Hiromitsu, Nagamune, Teruyuki
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801400/
https://ncbi.nlm.nih.gov/pubmed/28948469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-017-9768-7
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