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Mathematical Modeling of Protein Misfolding Mechanisms in Neurological Diseases: A Historical Overview

Protein misfolding refers to a process where proteins become structurally abnormal and lose their specific 3-dimensional spatial configuration. The histopathological presence of misfolded protein (MP) aggregates has been associated as the primary evidence of multiple neurological diseases, including...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Carbonell, Felix, Iturria-Medina, Yasser, Evans, Alan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801313/
https://ncbi.nlm.nih.gov/pubmed/29456521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00037
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