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Time-to-event data with time-varying biomarkers measured only at study entry, with applications to Alzheimer’s disease

Relating time-varying biomarkers of Alzheimer’s disease (AD) to time-to-event using a Cox model is complicated by the fact that AD biomarkers are sparsely collected, typically only at study entry; this is problematic since Cox regression with time-varying covariates requires observation of the covar...

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Bibliografske podrobnosti
izdano v:Stat Med
Main Authors: Lee, Catherine, Betensky, Rebecca A.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801265/
https://ncbi.nlm.nih.gov/pubmed/29266591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7547
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