Caveolin-Mediated Endocytosis of the Chlamydia M278 Outer Membrane Peptide Encapsulated in Poly(lactic acid)-Poly(ethylene glycol) Nanoparticles by Mouse Primary Dendritic Cells Enhances Specific Immune Effectors Mediated by MHC Class II and CD4+ T cells

We previously developed a Chlamydia trachomatis nanovaccine (PPM) by encapsulating a chlamydial M278 peptide within poly(lactic acid)-poly(ethylene glycol) biodegradable nanoparticles that immunopotentiated Chlamydia-specific immune effector responses in mice. Herein, we investigated the mechanistic...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Dixit, Saurabh, Sahu, Rajnish, Verma, Richa, Duncan, Skyla, Giambartolomei, Guillermo H., Singh, Shree. R., Dennis, Vida A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801148/
https://ncbi.nlm.nih.gov/pubmed/29324305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.12.019
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