Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo

Targeting host functions essential for viral replication has been considered as a broad spectrum and resistance-refractory antiviral approach. However, only a few host functions have, thus far, been validated as broad-spectrum antiviral targets in vivo. ER α-glucosidases I and II have been demonstra...

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Pubblicato in:Antiviral Res
Autori principali: Ma, Julia, Zhang, Xuexiang, Soloveva, Veronica, Warren, Travis, Guo, Fang, Wu, Shuo, Lu, Huagang, Guo, Jia, Su, Qing, Shen, Helen, Solon, Eric, Comunale, Mary Ann, Mehta, Anand, Guo, Ju-Tao, Bavari, Sina, Du, Yanming, Block, Timothy M., Chang, Jinhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800948/
https://ncbi.nlm.nih.gov/pubmed/29253498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2017.12.008
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