Glycation Reduces the Stability of ApoAI and Increases HDL Dysfunction in Diet-Controlled Type 2 Diabetes

CONTEXT: Hyperglycemia plays a key role in the pathogenesis of cardiovascular complications of diabetes. Type 2 diabetes mellitus (T2DM) is associated with high-density lipoprotein (HDL) dysfunction and increased degradation of apolipoprotein I (ApoAI). The mechanism(s) of these changes is largely u...

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Publicado en:J Clin Endocrinol Metab
Autores principales: Kashyap, Sangeeta R., Osme, Abdullah, Ilchenko, Serguei, Golizeh, Makan, Lee, Kwangwon, Wang, Shuhui, Bena, James, Previs, Stephen F., Smith, Jonathan D., Kasumov, Takhar
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2017
Materias:
Clinical Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800833/
https://ncbi.nlm.nih.gov/pubmed/29077935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2017-01551
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