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Microglia in Alzheimer’s disease

Proliferation and activation of microglia in the brain, concentrated around amyloid plaques, is a prominent feature of Alzheimer’s disease (AD). Human genetics data point to a key role for microglia in the pathogenesis of AD. The majority of risk genes for AD are highly expressed (and many are selec...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Hansen, David V., Hanson, Jesse E., Sheng, Morgan
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800817/
https://ncbi.nlm.nih.gov/pubmed/29196460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201709069
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