Control of microtubule dynamics using an optogenetic microtubule plus end–F-actin cross-linker

We developed a novel optogenetic tool, SxIP–improved light-inducible dimer (iLID), to facilitate the reversible recruitment of factors to microtubule (MT) plus ends in an end-binding protein–dependent manner using blue light. We show that SxIP-iLID can track MT plus ends and recruit tgRFP-SspB upon...

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Detaylı Bibliyografya
Yayımlandı:J Cell Biol
Asıl Yazarlar: Adikes, Rebecca C., Hallett, Ryan A., Saway, Brian F., Kuhlman, Brian, Slep, Kevin C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2018
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800807/
https://ncbi.nlm.nih.gov/pubmed/29259096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201705190
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