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Epigenetic regulation of HIV-1 latency: focus on polycomb group (PcG) proteins

HIV-1 latency allows the virus to persist until reactivation, in a transcriptionally silent form in its cellular reservoirs despite the presence of effective cART. Such viral persistence represents a major barrier to HIV eradication since treatment interruption leads to rebound plasma viremia. Polyc...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Khan, Sheraz, Iqbal, Mazhar, Tariq, Muhammad, Baig, Shahid M., Abbas, Wasim
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800276/
https://ncbi.nlm.nih.gov/pubmed/29441145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0441-z
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