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Hepatic stem cells with self-renewal and liver repopulation potential are harbored in CDCP1-positive subpopulations of human fetal liver cells

BACKGROUND: Mature human hepatocytes are critical in preclinical research and therapy for liver disease, but are difficult to manipulate and expand in vitro. Hepatic stem cells (HpSCs) may be an alternative source of functional hepatocytes for cell therapy and disease modeling. Since these cells pla...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Zhang, Ran-Ran, Zheng, Yun-Wen, Li, Bin, Nie, Yun-Zhong, Ueno, Yasuharu, Tsuchida, Tomonori, Taniguchi, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800061/
https://ncbi.nlm.nih.gov/pubmed/29402311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0747-3
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