Changes in the Cardiac GHSR1a-Ghrelin System Correlate With Myocardial Dysfunction in Diabetic Cardiomyopathy in Mice

Ghrelin and its receptor, the growth hormone secretagogue receptor 1a (GHSR1a), are present in cardiac tissue. Activation of GHSR1a by ghrelin promotes cardiomyocyte contractility and survival, and changes in myocardial GHSR1a and circulating ghrelin track with end-stage heart failure, leading to th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Endocr Soc
Prif Awduron: Sullivan, Rebecca, McGirr, Rebecca, Hu, Shirley, Tan, Alice, Wu, Derek, Charron, Carlie, Lalonde, Tyler, Arany, Edith, Chakrabarti, Subrata, Luyt, Leonard, Dhanvantari, Savita
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2017
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799831/
https://ncbi.nlm.nih.gov/pubmed/29450407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2017-00433
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