Changes in the Cardiac GHSR1a-Ghrelin System Correlate With Myocardial Dysfunction in Diabetic Cardiomyopathy in Mice

Ghrelin and its receptor, the growth hormone secretagogue receptor 1a (GHSR1a), are present in cardiac tissue. Activation of GHSR1a by ghrelin promotes cardiomyocyte contractility and survival, and changes in myocardial GHSR1a and circulating ghrelin track with end-stage heart failure, leading to th...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Sullivan, Rebecca, McGirr, Rebecca, Hu, Shirley, Tan, Alice, Wu, Derek, Charron, Carlie, Lalonde, Tyler, Arany, Edith, Chakrabarti, Subrata, Luyt, Leonard, Dhanvantari, Savita
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799831/
https://ncbi.nlm.nih.gov/pubmed/29450407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2017-00433
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