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In vitro RNA-seq-based toxicogenomics assessment shows reduced biological effect of tobacco heating products when compared to cigarette smoke

The battery of regulatory tests used to evaluate the risk of novel tobacco products such as heated tobacco products (THPs) presents some limitations including a bias towards the apical endpoint tested, and limited information on the mode of action. This is driving a paradigm shift to more holistic s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Haswell, Linsey E., Corke, Sarah, Verrastro, Ivan, Baxter, Andrew, Banerjee, Anisha, Adamson, Jason, Jaunky, Tomasz, Proctor, Christopher, Gaça, Marianna, Minet, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799303/
https://ncbi.nlm.nih.gov/pubmed/29402904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19627-0
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