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Generation of a rod-specific NRL reporter line in human pluripotent stem cells

Reporter lines generated in human pluripotent stem cells can be highly useful for the analysis of specific cell types and lineages in live cultures. We created the first human rod reporter line using CRISPR/Cas9 genome editing to replace one allele of the Neural Retina Leucine zipper (NRL) gene with...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Phillips, M. Joseph, Capowski, Elizabeth E., Petersen, Andrew, Jansen, Alex D., Barlow, Katherine, Edwards, Kimberly L., Gamm, David M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799252/
https://ncbi.nlm.nih.gov/pubmed/29402929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20813-3
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