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TNF-α/TNFR1 Signaling is Required for the Full Expression of Acute and Chronic Itch in Mice via Peripheral and Central Mechanisms

Increasing evidence suggests that cytokines and chemokines play crucial roles in chronic itch. In the present study, we evaluated the roles of tumor necrosis factor-alpha (TNF-α) and its receptors TNF receptor subtype-1 (TNFR1) and TNFR2 in acute and chronic itch in mice. Compared to wild-type (WT)...

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Detalhes bibliográficos
Publicado no:Neurosci Bull
Main Authors: Miao, Xiuhua, Huang, Ya, Liu, Teng-Teng, Guo, Ran, Wang, Bing, Wang, Xue-Long, Chen, Li-Hua, Zhou, Yan, Ji, Ru-Rong, Liu, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799114/
https://ncbi.nlm.nih.gov/pubmed/28365861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-017-0124-3
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