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MicroRNAs in CSF as prodromal biomarkers for Huntington disease in the PREDICT-HD study

OBJECTIVE: To investigate the feasibility of microRNA (miRNA) levels in CSF as biomarkers for prodromal Huntington disease (HD). METHODS: miRNA levels were measured in CSF from 60 PREDICT-HD study participants using the HTG protocol. Using a CAG–Age Product score, 30 prodromal HD participants were s...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Reed, Eric R., Latourelle, Jeanne C., Bockholt, Jeremy H., Bregu, Joli, Smock, Justin, Paulsen, Jane S., Myers, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798654/
https://ncbi.nlm.nih.gov/pubmed/29282329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000004844
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