Circulating insulin-like growth factors and Alzheimer disease: A mendelian randomization study

OBJECTIVE: To examine whether genetically predicted variation in circulating insulin-like growth factor 1 (IGF1) or its binding protein, IGFBP3, are associated with risk of Alzheimer disease (AD), using a mendelian randomization study design. METHODS: We first examined disease risk by genotypes of 9...

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Bibliographic Details
Published in:Neurology
Main Authors: Williams, Dylan M., Karlsson, Ida K., Pedersen, Nancy L., Hägg, Sara
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798653/
https://ncbi.nlm.nih.gov/pubmed/29282328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000004854
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