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Tandem synthesis of 1-formyl-1,2,3-triazoles

A tandem method for preparing 4-formyl-1,2,3-triazoles via a two-step one-pot acetal cleavage/CuAAC reaction was developed. Using this method, 4-formyl-1,2,3-triazole analogs with both electron-withdrawing and electron-donating substituents were prepared in good yield and purity. Expansion of this m...

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Détails bibliographiques
Publié dans:Tetrahedron Lett
Auteurs principaux: Fletcher, James T., Christensen, Joseph A., Villa, Eric M.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798646/
https://ncbi.nlm.nih.gov/pubmed/29422697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2017.10.023
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