Sustained-release of FGF-2 from a hybrid hydrogel of heparin-poloxamer and decellular matrix promotes the neuroprotective effects of proteins after spinal injury

INTRODUCTION: The short lifetime of protein-based therapies has largely limited their therapeutic efficacy in injured nervous post-spinal cord injury (post-SCI). METHODS: In this study, an affinity-based hydrogel delivery system provided sustained-release of proteins, thereby extending the efficacy...

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Udgivet i:Int J Nanomedicine
Main Authors: Xu, He-Lin, Tian, Fu-Rong, Xiao, Jian, Chen, Pian-Pian, Xu, Jie, Fan, Zi-Liang, Yang, Jing-Jing, Lu, Cui-Tao, Zhao, Ying-Zheng
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798566/
https://ncbi.nlm.nih.gov/pubmed/29440894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S152246
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