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Probing the Mechanism of LAL-32, a Gold Nanoparticle-Based Antibiotic Discovered through Small Molecule Variable Ligand Display

The unrelenting rise of antimicrobial-resistant bacteria has necessitated the search for novel antibiotic solutions. Herein we describe further mechanistic studies on a 2.0-nm-diameter gold nanoparticle-based antibiotic (designated LAL-32). This antibiotic exhibits bactericidal activity against the...

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Bibliografske podrobnosti
izdano v:Bioconjug Chem
Main Authors: Byrne-Nash, Rose, Lucero, Danielle M., Osbaugh, Niki A., Melander, Roberta J., Melander, Christian, Feldheim, Daniel L.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798254/
https://ncbi.nlm.nih.gov/pubmed/28636368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00199
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