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H(2)O(2) generation by BCG induces the cellular oxidative stress response required for BCG’s direct effects on urothelial carcinoma tumor biology

INTRODUCTION: Exposure of urothelial carcinoma (UC) cells to Bacille Calmette Guerin (BCG) affects cellular redox status and tumor cell biology but mechanism(s) remains unclear. This study examined free radical production by BCG, and in tumor cells in response to BCG, using global profiling of React...

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Detalhes bibliográficos
Publicado no:J Urol
Main Authors: Shah, Gopitkumar, Zielonka, Jacek, Chen, Fanghong, Zhang, Guangjian, Cao, YanLi, Kalyanaraman, Balaraman, See, William
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798233/
https://ncbi.nlm.nih.gov/pubmed/24928267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2014.05.115
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