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Effects of NMDA antagonists ketamine, methoxetamine and phencyclidine on the odor span test of working memory in rats

The glutamate hypothesis proposes that NMDA receptor hypofunction underlies cognitive and perhaps other schizophrenic symptoms. The present study used the odor span task to assess the effects of NMDA antagonists on remembering multiple stimuli in rodents. This task uses an incrementing non-matching-...

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Détails bibliographiques
Publié dans:Exp Clin Psychopharmacol
Auteurs principaux: Mathews, Michael J., Mead, Ralph N., Galizio, Mark
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797997/
https://ncbi.nlm.nih.gov/pubmed/29389166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/pha0000158
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