Inhibition of Glucose-6-Phosphate Dehydrogenase Reverses Cisplatin Resistance in Lung Cancer Cells via the Redox System

The pentose phosphate pathway (PPP), which branches from glycolysis, is correlated with cancer cell proliferation, survival and senescence. In this study, differences in the metabolic profile of the PPP and the redox status of human lung carcinoma A549 cells and cisplatin-induced multidrug-resistant...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Hong, Weipeng, Cai, Peiheng, Xu, Chuncao, Cao, Di, Yu, Weibang, Zhao, Zhongxiang, Huang, Min, Jin, Jing
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797786/
https://ncbi.nlm.nih.gov/pubmed/29445340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00043
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