Viscoelastic properties of human pancreatic tumors and in vitro constructs to mimic mechanical properties

Pancreatic ductal adenocarcinoma (PDAC) is almost universally fatal, in large part due to a protective fibrotic barrier generated by tumor-associated stromal (TAS) cells. This barrier is thought to promote cancer cell survival and confounds attempts to develop effective therapies. We present a 3D in...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Rubiano, Andres, Delitto, Daniel, Han, Song, Gerber, Michael, Galitz, Carly, Trevino, Jose, Thomas, Ryan M., Hughes, Steven J., Simmons, Chelsey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797706/
https://ncbi.nlm.nih.gov/pubmed/29191507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.11.037
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