Stability of the HTLV-1 Antisense-Derived Protein, HBZ, Is Regulated by the E3 Ubiquitin-Protein Ligase, UBR5

Human T-cell leukemia virus type 1 (HTLV-1) encodes a protein derived from the antisense strand of the proviral genome designated HBZ (HTLV-1 basic leucine zipper factor). HBZ is the only viral gene consistently expressed in infected patients and adult T-cell leukemia/lymphoma (ATL) tumor cell lines...

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Publicat a:Front Microbiol
Autors principals: Panfil, Amanda R., Al-Saleem, Jacob, Howard, Cory M., Shkriabai, Nikoloz, Kvaratskhelia, Mamuka, Green, Patrick L.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797633/
https://ncbi.nlm.nih.gov/pubmed/29441057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00080
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