Increasing Agrin Function Antagonizes Muscle Atrophy and Motor Impairment in Spinal Muscular Atrophy

Spinal muscular atrophy (SMA) is a pediatric genetic disease, characterized by motor neuron (MN) death, leading to progressive muscle weakness, respiratory failure, and, in the most severe cases, to death. Abnormalities at the neuromuscular junction (NMJ) have been reported in SMA, including neurofi...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Boido, Marina, De Amicis, Elena, Valsecchi, Valeria, Trevisan, Marco, Ala, Ugo, Ruegg, Markus A., Hettwer, Stefan, Vercelli, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797594/
https://ncbi.nlm.nih.gov/pubmed/29440993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00017
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