Red-light excitation of protoporphyrin IX fluorescence for subsurface tumor detection

OBJECTIVE: The objective of this study was to detect 5-aminolevulinic acid (ALA)-induced tumor fluorescence from glioma below the surface of the surgical field by using red-light illumination. METHODS: To overcome the shallow tissue penetration of blue light, which maximally excites the ALA-induced...

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Veröffentlicht in:J Neurosurg
Hauptverfasser: Roberts, David W., Olson, Jonathan D., Evans, Linton T., Kolste, Kolbein K., Kanick, Stephen C., Fan, Xiaoyao, Bravo, Jaime J., Wilson, Brian C., Leblond, Frederic, Marois, Mikael, Paulsen, Keith D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797501/
https://ncbi.nlm.nih.gov/pubmed/28777025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2017.1.JNS162061
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