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Methylation of the genes ROD1, NLRC5, and HKR1 is associated with aging in Hainan centenarians

BACKGROUND: Human aging is a hot topic in biology, and it has been associated with DNA methylation changes at specific genomic sites. We aimed to study the changes of DNA methylation at a single-CpG-site resolution using peripheral blood samples from centenarians. METHODS: Using Illumina 450 K Methy...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Zeng, Qian, Chen, Xiaoping, Ning, Chaoxue, Zhu, Qiao, Yao, Yao, Zhao, Yali, Luan, Fuxin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797414/
https://ncbi.nlm.nih.gov/pubmed/29394898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0334-1
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