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TRPA1-dependent reversible opening of tight junction by natural compounds with an α,β-unsaturated moiety and capsaicin

The delivery of hydrophilic macromolecules runs into difficulties such as penetration of the cell membrane lipid bilayer. Our prior experiment demonstrated that capsaicin induces the reversible opening of tight junctions (TJs) and enhances the delivery of hydrophilic macromolecules through a paracel...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kanda, Yusuke, Yamasaki, Youhei, Sasaki-Yamaguchi, Yoshie, Ida-Koga, Noriko, Kamisuki, Shinji, Sugawara, Fumio, Nagumo, Yoko, Usui, Takeo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797179/
https://ncbi.nlm.nih.gov/pubmed/29396565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20526-7
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