PCSK9 induces a pro-inflammatory response in macrophages

Intraplaque release of inflammatory cytokines from macrophages is implicated in atherogenesis by inducing the proliferation and migration of media smooth muscle cells (SMCs). PCSK9 is present and released by SMCs within the atherosclerotic plaque but its function is still unknown. In the present stu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ricci, Chiara, Ruscica, Massimiliano, Camera, Marina, Rossetti, Laura, Macchi, Chiara, Colciago, Alessandra, Zanotti, Ilaria, Lupo, Maria Giovanna, Adorni, Maria Pia, Cicero, Arrigo F. G., Fogacci, Federica, Corsini, Alberto, Ferri, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797178/
https://ncbi.nlm.nih.gov/pubmed/29396513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20425-x
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