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Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice

Major depressive disorder is associated with abnormalities in the brain and the immune system. Chronic stress in animals showed that epigenetic and inflammatory mechanisms play important roles in mediating resilience and susceptibility to depression. Here, through a high-throughput screening, we ide...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Nat Commun
Κύριοι συγγραφείς: Wang, Jun, Hodes, Georgia E., Zhang, Hongxing, Zhang, Song, Zhao, Wei, Golden, Sam A., Bi, Weina, Menard, Caroline, Kana, Veronika, Leboeuf, Marylene, Xie, Marc, Bregman, Dana, Pfau, Madeline L., Flanigan, Meghan E., Esteban-Fernández, Adelaida, Yemul, Shrishailam, Sharma, Ali, Ho, Lap, Dixon, Richard, Merad, Miriam, Han, Ming-Hu, Russo, Scott J., Pasinetti, Giulio M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797143/
https://ncbi.nlm.nih.gov/pubmed/29396460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02794-5
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