The inhibition of PLCγ1 protects chondrocytes against osteoarthritis, implicating its binding to Akt

Previous studies have addressed the involvement of phosphoinositide-specifc phospholipase γ1 (PLCγ1) and protein kinase B (PKB/Akt) in osteoarthritis (OA) pathogenesis, but it is not ascertained the possibility of them to be potential targets for OA therapy. Here, through local intra-articular injec...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cai, Heguo, Qu, Ning, Chen, Xiaolei, Zhou, Yang, Zheng, Xinpeng, Zhang, Bing, Xia, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796987/
https://ncbi.nlm.nih.gov/pubmed/29435116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23286
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