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Vacuole-inducing compounds that disrupt endolysosomal trafficking stimulate production of exosomes by glioblastoma cells

Exosomes are produced from mammalian cells when multivesicular endosomes fuse with the plasma membrane, releasing their intralumenal vesicles. In this study we assessed the effects of MOPIPP, a novel indole-based chalcone, and vacuolin-1, a distinct triazine-based compound, on exosome production in...

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Detalhes bibliográficos
Publicado no:Mol Cell Biochem
Main Authors: Li, Zehui, Mbah, Nneka E., Maltese, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796851/
https://ncbi.nlm.nih.gov/pubmed/28770472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-017-3130-x
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