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Reversible DNA-protein cross-linking at epigenetic DNA marks

5-Formylcytosine (5fC) is an endogenous DNA modification frequently found within regulatory elements of mammalian genes. Although 5fC is an oxidation product of 5-methylcytosine (5mC), the two epigenetic marks show distinct genome-wide distributions and protein affinities, suggesting that they perfo...

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Bibliographic Details
Published in:Angew Chem Int Ed Engl
Main Authors: Ji, Shaofei, Shao, Hongzhao, Han, Qiyuan, Seiler, Christopher L., Tretyakova, Natalia Y.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796521/
https://ncbi.nlm.nih.gov/pubmed/28898504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201708286
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