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Differential Selective Pressures Experienced by the Aurora Kinase Gene Family

Aurora kinases (AKs) are serine/threonine kinases that are essential for cell division. Humans have three AK genes: AKA, AKB, and AKC. AKA is required for centrosome assembly, centrosome separation, and bipolar spindle assembly, and its mutation leads to abnormal spindle morphology. AKB is required...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Seeling, Joni M., Farmer, Alexis A., Mansfield, Adam, Cho, Hyuk, Choudhary, Madhusudan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796022/
https://ncbi.nlm.nih.gov/pubmed/29283376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19010072
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