Intracellular Renin Inhibits Mitochondrial Permeability Transition Pore via Activated Mitochondrial Extracellular Signal-Regulated Kinase (ERK) 1/2 during Ischemia in Diabetic Hearts

Although beneficial effects of non-secreting intracellular renin (ns-renin) against ischemia have been reported, the precise mechanism remains unclear. In this study, we investigated the roles of ns-renin and mitochondrial extracellular signal-related kinase (ERK) 1/2 on mitochondrial permeability t...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Satoh, Terumori, Saotome, Masao, Katoh, Hideki, Nonaka, Daishi, Hasan, Prottoy, Hayashi, Hideharu, Maekawa, Yuichiro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796005/
https://ncbi.nlm.nih.gov/pubmed/29295576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19010055
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