Inhibition of Aquaporin-4 Improves the Outcome of Ischaemic Stroke and Modulates Brain Paravascular Drainage Pathways

Aquaporin-4 (AQP4) is the most abundant water channel in the brain, and its inhibition before inducing focal ischemia, using the AQP4 inhibitor TGN-020, has been showed to reduce oedema in imaging studies. Here, we aimed to evaluate, for the first time, the histopathological effects of a single dose...

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Publicat a:Int J Mol Sci
Autors principals: Pirici, Ionica, Balsanu, Tudor Adrian, Bogdan, Catalin, Margaritescu, Claudiu, Divan, Tamir, Vitalie, Vacaras, Mogoanta, Laurentiu, Pirici, Daniel, Carare, Roxana Octavia, Muresanu, Dafin Fior
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795996/
https://ncbi.nlm.nih.gov/pubmed/29295526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19010046
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