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Mesenchymal Stem Cell–Derived Small Extracellular Vesicles Promote Neuroprotection in Rodent Models of Glaucoma

PURPOSE: To investigate the benefit of bone marrow mesenchymal stem cell (BMSC)-derived small extracellular vesicles (sEV) as an intravitreal (ivit) therapy in two rat models of glaucoma and to determine and identify candidate miRNA involved in the mechanism. METHODS: sEV were isolated from human BM...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Mead, Ben, Amaral, Juan, Tomarev, Stanislav
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795911/
https://ncbi.nlm.nih.gov/pubmed/29392316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22855
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