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Metadherin contributes to epithelial-mesenchymal transition and paclitaxel resistance induced by acidic extracellular pH in nasopharyngeal carcinoma

Paclitaxel resistance is a challenge to the treatment of nasopharyngeal carcinoma (NPC). An acidic extracellular pH (pH(e)), a hallmark of solid tumors, is demonstrated to decrease the efficacy of chemotherapy. However, the precise function of acidic pH(e) in mediating chemotherapy in NPC remains un...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Yu, Changyun, Liu, Yong, Qin, Zhaobing
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795829/
https://ncbi.nlm.nih.gov/pubmed/29456735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.7760
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