The Role of E6 Spliced Isoforms (E6*) in Human Papillomavirus-Induced Carcinogenesis

Persistent infections with High Risk Human Papillomaviruses (HR-HPVs) are the main cause of cervical cancer development. The E6 and E7 oncoproteins of HR-HPVs are derived from a polycistronic pre-mRNA transcribed from an HPV early promoter. Through alternative splicing, this pre-mRNA produces a vari...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Olmedo-Nieva, Leslie, Muñoz-Bello, J. Omar, Contreras-Paredes, Adriana, Lizano, Marcela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795458/
https://ncbi.nlm.nih.gov/pubmed/29346309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10010045
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