Extended Linkers Improve the Detection of Protein-protein Interactions (PPIs) by Dihydrofolate Reductase Protein-fragment Complementation Assay (DHFR PCA) in Living Cells

Understanding the function of cellular systems requires describing how proteins assemble with each other into transient and stable complexes and to determine their spatial relationships. Among the tools available to perform these analyses on a large scale is Protein-fragment Complementation Assay ba...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Chrétien, Andrée-Ève, Gagnon-Arsenault, Isabelle, Dubé, Alexandre K., Barbeau, Xavier, Després, Philippe C., Lamothe, Claudine, Dion-Côté, Anne-Marie, Lagüe, Patrick, Landry, Christian R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Technological Innovation and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795398/
https://ncbi.nlm.nih.gov/pubmed/29203496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR117.000385
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