Genetic risk, dysbiosis, and treatment stratification using host genome and gut microbiome in inflammatory bowel disease

OBJECTIVES: Inflammatory bowel diseases (IBD), comprised of Crohn’s disease (CD) and ulcerative colitis (UC), are characterized by a complex pathophysiology that is thought to result from an aberrant immune response to a dysbiotic luminal microbiota in genetically susceptible individuals. New techno...

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Detalhes bibliográficos
Publicado no:Clin Transl Gastroenterol
Main Authors: Moustafa, Ahmed, Li, Weizhong, Anderson, Ericka L, Wong, Emily H M, Dulai, Parambir S, Sandborn, William J, Biggs, William, Yooseph, Shibu, Jones, Marcus B, Venter, J Craig, Nelson, Karen E, Chang, John T, Telenti, Amalio, Boland, Brigid S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
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Original Contributions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795019/
https://ncbi.nlm.nih.gov/pubmed/29345635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2017.58
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