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Probing the folding pathway of a consensus serpin using single tryptophan mutants

Conserpin is an engineered protein that represents the consensus of a sequence alignment of eukaryotic serpins: protease inhibitors typified by a metastable native state and a structurally well-conserved scaffold. Previously, this protein has been found to adopt a native inhibitory conformation, pos...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Yang, Li, Irving, James A., Dai, Weiwen, Aguilar, Marie-Isabel, Bottomley, Stephen P.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794792/
https://ncbi.nlm.nih.gov/pubmed/29391487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19567-9
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