Therapeutic effects of anti-CD154 antibody in cynomolgus monkeys with advanced rheumatoid arthritis

Rheumatoid arthritis is one major chronic inflammatory systemic autoimmune disease. The CD154-CD40 interactions play a critical role in the regulation of immune responses and the maintenance of autoimmunity. Therefore, we aimed to determine whether anti-CD154 antibody treatment show positive effects...

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Udgivet i:Sci Rep
Main Authors: Choi, Eun Wha, Lee, Kyo Won, Park, Hyojun, Kim, Hwajung, Lee, Jong Hyun, Song, Ji Woo, Yang, Jehoon, Kwon, Yeongbeen, Kim, Tae Min, Park, Jae Berm, Kim, Sungjoo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794761/
https://ncbi.nlm.nih.gov/pubmed/29391506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20566-z
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