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High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer
The gene encoding the ATPase of the chromatin remodeling SWI/SNF complexes SMARCA4 (BRG1) is often mutated or silenced in tumors, suggesting a role as tumor suppressor. Nonetheless, recent reports show requirement of SMARCA4 for tumor cells growth. Here, we performed a computational meta-analysis us...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5794756/ https://ncbi.nlm.nih.gov/pubmed/29391527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20217-3 |
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