Neutrophil peptidyl arginine deiminase-4 has a pivotal role in ischemia/reperfusion-induced acute kidney injury

Ischemia/reperfusion is a common cause of acute kidney injury (AKI). However, mechanisms underlying the sudden loss in kidney function and tissue injury remain to be fully elucidated. Here, we investigated the role of peptidyl arginine deiminase-4 (PAD4), which converts arginine to citrulline and pl...

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Veröffentlicht in:Kidney Int
Hauptverfasser: Raup-Konsavage, Wesley M., Wang, Yanming, Wang, Wei Wei, Feliers, Denis, Ruan, Hong, Reeves, W. Brian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794573/
https://ncbi.nlm.nih.gov/pubmed/29061334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.08.014
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