DHX15 promotes prostate cancer progression by stimulating Siah2-mediated ubiquitination of androgen receptor

Androgen receptor (AR) activation is critical for prostate cancer development and progression, including castration-resistance. The nuclear export signal of AR (NES(AR)) plays an important role in AR intracellular trafficking and proteasome-dependent degradation. Here, we identified the RNA helicase...

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Bibliografske podrobnosti
izdano v:Oncogene
Main Authors: Jing, Yifeng, Nguyen, Minh M., Wang, Dan, Pascal, Laura E., Guo, Wenhuan, Xu, Yadong, Ai, Junkui, Deng, Fang-Ming, Masoodi, Khalid Z., Yu, Xinpei, Zhang, Jian, Nelson, Joel B., Xia, Shujie, Wang, Zhou
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794523/
https://ncbi.nlm.nih.gov/pubmed/28991234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.371
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