Reversible Age-Related Phenotypes Induced during Larval Quiescence in C. elegans

Cells can enter quiescent states in which cell cycling and growth are suspended. We find that during a long developmental arrest (quiescence) induced by starvation, newly-hatched C. elegans acquire features associated with impaired proteostasis and aging: mitochondrial fission, ROS production, prote...

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Bibliografiske detaljer
Udgivet i:Cell Metab
Main Authors: Roux, Antoine E., Langhans, Kelley, Huynh, Walter, Kenyon, Cynthia
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794336/
https://ncbi.nlm.nih.gov/pubmed/27304510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.05.024
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