Impact of treatment and re-treatment with artemether-lumefantrine and artesunate-amodiaquine on selection of Plasmodium falciparum multidrug resistance gene-1 polymorphisms in the Democratic Republic of Congo and Uganda

BACKGROUND: The emergence of resistance against artemisinin combination treatment is a major concern for malaria control. ACTs are recommended as the rescue treatment, however, there is limited evidence as to whether treatment and re-treatment with ACTs select for drug-resistant P. falciparum parasi...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Baraka, Vito, Mavoko, Hypolite Muhindo, Nabasumba, Carolyn, Francis, Filbert, Lutumba, Pascal, Alifrangis, Michael, Van geertruyden, Jean-Pierre
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794077/
https://ncbi.nlm.nih.gov/pubmed/29390014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191922
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