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Detection and Mapping of DNA Methylation with 2D Material Nanopores

DNA methylation is an epigenetic modification involving the addition of a methyl group to DNA, which is heavily involved in gene expression and regulation, thereby critical to the progression of diseases such as cancer. In this work we show that detection and localization of DNA methylation can be a...

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Bibliografiske detaljer
Udgivet i:NPJ 2D Mater Appl
Main Authors: Qiu, Hu, Sarathy, Aditya, Schulten, Klaus, Leburton, Jean-Pierre
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794036/
https://ncbi.nlm.nih.gov/pubmed/29399640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41699-017-0005-7
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